DNA Fragmentation & Degradation Overview

The ability to fragment and degrade DNA has been available for years. However, with recent discoveries in the field of epigenetics, this technology can be applied in order to determine methylated and hydroxymethylated modifications of sheared DNA, nucleotides or nucleosides. Fragmented and degraded DNA is ideal for a number of downstream applications including Next-Gen sequencing, LC/Mass spectrometry, thin layer chromatography, and immunoprecipitation.