Sample Collection & Stabilization Overview
RNA is susceptible to degradation by exposure to ubiquitous ribonucleases, elevated temperatures, pH extremes, and other harsh conditions. The stabilization of intact RNA is a key factor that determines the quality and consistency of downstream RNA isolation and analyses. Improper sample collection and storage can dramatically and irreversibly compromise the integrity of RNA.
DNA/RNA Shield™ is an all-in-one reagent for sample collection and worry-free RNA (and DNA) stabilization at ambient temperatures. DNA/RNA Shield™ completely inactivates RNases and infectious agents, and is compatible with all RNA purification methods. Use DNA/RNA Shield™ with multiple collection devices and samples including swabs, cells, tissues, biological liquid samples, and more! DNA/RNA Shield™ instantly lyses cells, ensures RNA stability, and preserves expression profiles during transport and/or long-term storage at ambient temperatures – without the need for cold storage or specialized equipment. Samples in DNA/RNA Shield™ can be added directly to most of Zymo Research's RNA purification kits, unlike other reagents, which require complicated and time-consuming removal steps.