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Small & microRNA Isolation Overview

The importance of miRNAs and other small RNAs in regulating gene expression and other cellular processes is clear, but many kits from other companies do not effectively recover miRNAs and other small RNA molecules.  In addition, many small RNAs are expressed at low abundance, or only in specific cell types. To obtain results you can trust, you need to recover ALL small RNAs during your purification. The RNA isolation kits from Zymo Research efficiently recover small RNA molecules as short as 17 nucleotides.

Small & microRNA Isolation Technologies

RNA from TRIzol®/TRI-Reagent®

Spin column- and plate-based isolation of total RNA (including microRNA ≥17 nt) directly from TRI Reagent®, TRIzol®, and all other acid-guanidinium-phenol based reagents without conventional phase separation or precipitation steps! DNase I included.

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Cells and Tissue

Non-organic isolation of total, small (microRNA), or large RNA from cultured cells, tissue samples, buccal cells, buffy coat, plasma, serum, and other biological liquids.

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Polyacrylamide Gels

Extraction and concentration of high quality small RNAs (including microRNA) from polyacrylamide gels (native or denatured).

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