Genome-wide 5-hmC Analysis
Zymo Research is proud to offer the first of its kind service for genome-wide investigation of the sixth base, 5-hydroxymethylcytosine (5-hmC) as the latest addition to its portfolio of consolidated epigenetic service solutions. The new genome-wide 5-hmC analysis platform features cutting-edge 5-hmC DNA enrichment, library prep, and next-generation sequencing technologies to ensure the sensitivity of 5-hmC detection in genome-wide context.
Features include:
I. Unparalleled specificity and sensitivity: Featured JBP-1 capture technology provides unparalleled enrichment of 5-hmC DNA. This ensures high-resolution output and far greater detection than methods featuring antibody-based enrichment schemes. The technology facilitates more data from less input (sub-microgram DNA) and allows 5-hmC to be distinguished from 5-methylcytosine (5-mC) marks
II. Fully customizable bioinformatics pipeline: Facilitated by a novel, straightforward bioinformatics solution is the quick and accurate transformation of raw sequence data into annotated genome tracks, with options including concatenated gene profiles, read distributions, coverage data, and more. Summarizing these data is a consolidated report delivered to the customer comprised of a project synopsis and publication-ready figures and graphs.
For pricing information and a personalized quote please fill out a service inquiry form or call us at (949) 679-1190 or toll-free at (888) 882-9682.
5-hmC Service Inquiry
Also, other epigenetic services are available including genome-wide and whole genome methylation analysis, locus-specific validation via direct bisulfite sequencing, and global 5-mC and 5-hmC quantitation by mass spectroscopy determination... please inquire.
