The Microbiomics Suite of Services
Next-Gen Sequencing Services for Discovery, Identification, and Characterization of Microbial Communities
- Zymo Research offers the most comprehensive services for 16S rRNA and shotgun sequencing from any sample type
- ZymoBIOMICS Services are validated using the ZymoBIOMICS™ Microbial Community Standards for unbiased, publication-quality data
- Services include low-bioburden processing and accurate DNA/RNA isolation using the ZymoBIOMICS™ product line for the most accurate taxonomic profiling
Why consider a Next-Gen Sequencing approach to analyze microbial communities?
Because many microbes can't be cultured and are missed using conventional analysis techniques.
Using Next-Gen Sequencing it is possible accurately assess entire microbial communities (microbiomes) using targeted (16S rRNA gene) or whole genome sequencing without the need for culturing.
Molecular biology is currently being revolutionized by whole-genome sequencing of individual microorganisms, as well as entire microbial communities (microbiomes), a field known as metagenomics. With direct access to the genomes of microorganisms in their natural habitat, metagenomics has been applied in environmental studies as well as biomarker research and has opened a new era in the study of microbial diversity.
Zymo Research offers state-of-the-art pipelines for sample collection, nucleic acid isolation, and library preparation for superior quality sequencing and analysis. The entire workflow is validated using the ZymoBIOMICS™ Microbial Community Standards and provides non-biased analysis.
Validated, Non-Biased Workflows from Collection to Analysis
Unlike other providers, the entire process (from extraction to final analysis) can take place at Zymo Research ensuring customers' samples are always accounted for.
ZymoBIOMICS™ Services are validated using the ZymoBIOMICS™ Microbial Community Standards for unbiased, accurate community profiling
Zymo Research provides comprehensive Next-Gen Sequencing services to detect microorganisms that inhabit animals, plants, and environmental samples.
Human Microbiomics (Gut & Skin)
Water & Soil Testing
16s rRNA Gene Analysis
Barchart of Microbial Composition
Microbial composition (genus level) and abundance within four samples. Each colored band in a column represents the genus of a microorganism and the band width shows its relative abundance.
Hierarchical Clustering of Samples
The clustering plot above shows the relationship of microbial diversity between six environmental samples. Soil and Lake samples are observed to be more similar to one another and less similar to Ocean samples.
Alpha Diversity (within-sample)
The box plot shows the alpha diversity score for two gut samples from three individual mice. The higher the score, the more diverse the microbial composition.
Beta Diversity (between-sample)
The box plot displays the beta diversity (distance) for gut samples of the three mice. Distances between samples are indicative of the similarity between samples from the same mouse versus the diversity between samples from different mice.