ZymoBIOMICS Services

Computer with graphs on screen
  • Complete Solution for Unbiased Microbiome Profiling
  • Quick Turnaround as Little as 2 Weeks
  •  Species-Level Resolution with 16S Sequencing

Focus on discoveries. We take care of everything else.

Comprehensive & User-Friendly Report

Let Us Do the Work.

Microbiome Report Computer
Microbiome Reports

Get all the data in a single, comprehensive report.

Publication-Ready Data at Your Fingertips

All ZymoBIOMICS Services include comprehensive bioinformatics and statistical analyses for each microbiomics project. The report can be customized according to each unique project or application. Let Zymo Research do the bioinformatics so that you don’t have to!

Varies Graph

Typical Analyses Include:

  • Composition Bar Plots
  • Taxonomy Heatmap
  • Alpha-Diversity
  • Beta-Diversity
  • LEfSe Biomarker Discovery
  • Taxa2SV Decomposer

View an Example Report:

Take a look at a project analyzing human stool samples with 16S sequencing by downloading the sample report.

Cited in Major Publications

Read peer-reviewed citations to discover how scientists are using these services.

Microbiomics-Grade Technologies

Any sample. Ultra-clean. Rigorous controls.

Infinity Dna

Human samples, water, soil, food testing , pathogen surveillance

Certification Of Ultra-Clean Certified

Low Bioburden Reagents limit sample contamination.

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Zymo's mock communities deemed "Regulatory-grade genomes" by FDA

Reliable and Unmatched Sample Processing

Zymo Research was the first company to develop microbiomics solutions, from collection to conclusion, based on new rigorous standards for microbiome measurements. Zymo Research is leading the initiative to improve reproducibility and accuracy in the field by developing the first commercially available microbiome standards. The FDA has accepted the ZymoBIOMICS Microbial Community standards as Regulatory-Grade Genomes in the Database for Reference Grade Microbial Sequences (FDA-ARGOS).The standards are utilized to develop and optimize every step of the microbiomics workflow, ensuring high-quality, unbiased results.

Sampling of different samples
Unbiased Microbiome Profiling

Microbiome Standards Included in Every Project.

microbiome composition graph

All Sources of Bias Taken Into Account

Microbiome graph with unbiased and biased results
Zymo Research’s unparalleled DNA extraction protocols, commonly reported in literature, are certified to have unbiased microbial lysis and minimize bias during DNA extraction. Common DNA extraction protocols reported in literature are found to have a dramatic bias as demonstrated in the figure above.
Preserve Microbiome Samples at Ambient Temperature with DNA/RNA Shield
Microbiome Fecal Sample graph
Various sample collection devices prefilled with DNA/RNA Shield are available to help streamline your collection process.
Controlling PCR Chimera during 16S Library Preparation
Microbiome Quick 16S graph
The innovative use of real-time PCR during library preparation minimizes PCR chimera formation.
Redefining targeted sequencing

Species-Level Resolution with 16S Sequencing.

Species level Pie Chart
species level chart

Reshape the Coverage of 16S Primers

Microbiome Reshape Chart
The phylogenetic coverage of 16S sequencing is determined by the selection of general bacterial 16S primers used. As more microbes are newly discovered, the design of 16S primer sets becomes even more critical to successful coverage of sample composition. The 16S primers designed by Zymo Research significantly improve coverage of primers targeting V1-V2 and V3-V4 regions. These two regions confer higher taxonomy resolution than the V4 region.
ZymoBIOMICS Shotgun Service

Take your samples further.


Microbiome CosmosID

ZymoBIOMICS Shotgun Service

Shotgun metagenomic sequencing offers strain-level resolution, multiple-kingdom identification, and functional profiling.

In partnership with CosmosID, Zymo Research provides the most complete and sophisticated solution for shotgun metagenomics. The bioinformatics analysis for the ZymoBIOMICS Shotgun Service features:

Performance

  • Identification with industry-leading sensitivity and precision
  • Strain-level resolution of all microbial kingdoms (bacteria, archaea, viruses, protists, fungi)
Microbiome Shotgun Service

World’s largest curated and customizable databases

  • 150,000+ genomes and gene sequences
  • 100s of millions of biomarkers
  • Data structure follows the phylogenetic hierarchy of genomes, enabling accurate classification, even of unknown strains, based on this virtual tree of life
  Target Organisms Sequencing Platform Price Per Sample*
ZymoBIOMICS Targeted Sequencing Service: 16S (V1-V2, V3-V4, V4, or V6-V8) Bacteria, Archaea Illumina MiSeq ≤ $100
ZymoBIOMICS Targeted Sequencing Service: ITS Fungi Illumina MiSeq ≤ $100
ZymoBIOMICS Targeted Sequencing Service: 18S Eukaryotes Illumina MiSeq ≤ $100
ZymoBIOMICS Shotgun Metagenomic Service Bacteria, Viruses, Fungi, Protists Illumina HiSeq ≤ $300

*Pricing based on the number of samples and type of service requested. Please inquire for more information for your specific project.

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