Epigenetic regulation refers to biological mechanisms in which DNA, RNA, and proteins are chemically or structurally modified, without changing their primary sequence. These epigenetic modifications play critical roles in the regulation of numerous cellular processes, including gene expression, DNA replication, and recombination. Epigenetic regulatory mechanisms include DNA methylation and hydroxymethylation, histone modification, chromatin remodeling, RNA methylation, and regulation by small and long non-coding RNAs. While epigenetic modifications can be very stable and passed on to multiple generations in some cases, they can also dynamically change in response to specific cellular conditions or environmental stimuli. When epigenetic mechanisms are misregulated, the result can be detrimental to health and can lead to cancer, neurological disorders, and developmental abnormalities. Therefore, epigenetic modifications are emerging as important diagnostic and prognostic biomarkers in many fields of medicine.
In recent years, epigenetics has exploded into one of the most exciting and rapidly expanding fields in biology. Zymo Research has grown with it, becoming The Epigenetics Company™. Zymo Research understands the need for high-quality and reliable products for epigenetics research, and we offer an extensive and continually growing line of products, kits, and genome-wide services to facilitate investigations into epigenetic regulation of cellular processes. We are committed to continue meeting the needs of epigenetic researchers into the future.