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EpiBeat - The Latest in Epigenetics News
Epigenetic Marks Associated to Severe Obesity
There is growing evidence that DNA methylation might contribute to obesity. Candidate gene methylation studies in animal models and humans have demonstrated methylation changes in promoters of various genes that are implicated in obesity,... [Read more on EpiBeat]
CHL1 Hypermethylation in Breast Cancer
Breast cancer (BC) is the most common cancer among women and one of the leading causes of cancer-related deaths worldwide (1-3). It is a clinically heterogeneous disease, with at least 5 different subtypes (4) and quite variable prognosis,... [Read more on EpiBeat]
Epigenetic Predisposition to Radiation Fibrosis
Radiotherapy is a highly efficient treatment for many cancers including breast cancer. Intraoperative radiotherapy (IORT), a relatively new type of radiation therapy, has proven successful as a curative treatment for early cancer stages.... [Read more on EpiBeat]
Transient Imprinting of Genes in the Human Placenta
When the fertilization occurs, the maternal and paternal pronuclei have thousands of opposite methylated regions. Most of this germline methylation are resolved during the postfertilization epigenetic reprogramming by active mechanism... [Read more on EpiBeat]
Epigenetic Diagnostics: Locus-specific DNA Methylation Testing Poised for Clinical Impact
Precision medicine holds great potential to make a direct positive impact in the clinic. A growing number of diagnostic panels addressing a list of disease indications are now available for testing. Currently most tests are designed... [Read more on EpiBeat]
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