Elevating Plasmid Purification

Next level plasmid purification is within reach thanks to Zymo Research's innovative solutions for the rapid recovery of high-yield, transfection-grade plasmid.

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Simplify the Preparation of Transfection-Grade Plasmid

Our ZymoPURE™ products were developed to help you achieve highly concentrated endotoxin-free plasmid in just minutes using an easy spin-column protocol.

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Sweet High-Throughput Purification

Introducing the ZymoPURE™ 96 Plasmid Miniprep Kit, a high-throughput method for the purification of up to 100 µg of ultra-pure transfection-grade plasmid DNA.

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Building Better Recombinant Antibody Factories

Researchers are using novel plasmid purification technology and mammalian expression systems to overcome the drawbacks of expressing human proteins in E. coli.

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Elevating Plasmid Purification

Transfection-Grade Plasmid Simplified

Sweet High-Throughput Purification

Building Better Antibody Factories

Plasmid Purification Reinvented

Plasmid DNA has proven to be an indispensable biological tool with a wide range of applications, this includes understanding genes at their most basic level to potential therapies for human diseases. Scientists at Zymo understand that the success of the downstream experiment starts with effective plasmid purification and have carefully developed plasmid purification technologies with this in mind, enabling breakthroughs in everything from neuroscience to vaccine development. Zymo Research's novel plasmid purification technologies are designed to efficiently concentrate plasmid while removing contaminants like RNA, genomic DNA, endotoxins, salts, and proteins. The result - high-yield, transfection-grade plasmids at your fingertips.

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Knowledge Center

How To Increase Plasmid Yield

Whether you're dealing with low copy numbers, low culture density, or culture overgrowth, this guide will help you determine the best way to boost your plasmid yield from E. coli cultures.

Dos & Don'ts of Plasmid Purification

Looking for some tips for effective plasmid purification? This guide highlights some of the essential Dos and Don'ts of plasmid purification.

Making Plasmid Purification Pretty and Practical

Read on to learn how Zymo's patented color-coded buffer system emerged, enabling easier distinction between buffers and improved visualization of lysis & neutralization steps.

Minimizing CRISPR Off-target Effects

CRISPR is changing the gene therapy game, but off-target effects are a major concern. Read on to learn about the novel tools that can identify potential off-target sites and help researchers better evaluate risk.

Is Plasmid DNA Quality Affecting your Transfections?

Transfection success is highly dependent on the purity and quality of the plasmid DNA being used. This blog highlights four key points to consider for ensuring successful transfections.

3 Things to Know for Making Competent Cells

Making highly competent cells is critical to a successful transformation. Follow this guide for some tips to maximize the transformation efficiency of your competent cells.

Solutions for Plasmid DNA

Plasmid Purification

Recover Ultra-Pure, High-Yield Plasmid in Minutes

Competent Cells

Highly Efficient Cloning & Protein Expression

DNA Clean-Up & Concentration

Achieve Unrivaled Purity and Concentrations

DNA Analysis

Robust & Affordable Products for Routine Analysis

Yeast

Highly Effective Yeast-Centered Research Solutions

RNA Extraction

Total RNA Purification from any sample, NGS Ready

NGS Services

State-of-the-art sample processing workflows and cutting-edge bioinformatics

Promotions

Save 30% + Get a Free T-Shirt

Enjoy 30% off customizable product bundles for Molecular Cloning, Protein & Enzymes, and Synthetic Biology. Plus, get a free limited-edition T-shirt!

Promo Codes:

  • CLONING30
  • PROTEIN30
  • SYNBIO30

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Zymo Research - E. coli I'm Competent Promotion T-shirt

30% OFF ALL Purification Kits + FREE Cozy Sweater

Fall into 30% savings on all DNA and RNA purification kits with Promo Code: POWER30 and get inhibitor-free DNA and RNA from any sample. Plus, enjoy a seasonal limited-edition sweater with any order over $1,250.

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Zymo Research - E. coli I'm Competent Promotion T-shirt

Featured Technologies

Highly Cited
Plasmid Purification

ZymoPURE II Plasmid Maxiprep Kit

Achieve up to 3 mg of Endotoxin-Free Plasmid in 16 minutes

Purify highly concentrated endotoxin-free plasmid DNA from up to 150 ml of E. coli culture using a simple and fast spin-column protocol.

Trending
Competent Cells

Mix & Go! Competent Cells

Simple 20 Second E. coli Transformations

E. coli transformation without the need for heat shock, lengthy incubations, or outgrowth procedures. Just add DNA and spread on plate.

Popular
Plasmid Purification

ZymoPURE Plasmid Miniprep Kit

Purify up to 100 µg of Transfection-Grade Plasmid with a Miniprep

Simple spin-column purification of highly concentrated transfection-grade plasmid DNA from up 5 ml of E. coli culture.

Most Cited
Plasmid Purification

ZymoPURE II Plasmid Midiprep Kit

Achieve up to 1.2 mg of Endotoxin-Free Plasmid in 16 minutes

Purify highly concentrated endotoxin-free plasmid DNA from up to 50 ml of E. coli culture using a simple and fast spin-column protocol.

Most Cited
DNA Clean-Up

Zymoclean Gel DNA Recovery Kit

Recover highly concentrated DNA from agarose gel in just minutes

Simple and efficient protocol for isolating up to 5 µg of highly concentrated and ultra-pure DNA from agarose gel excisions using Zymo-Spin technology.

Trending
Plasmid Purification

ZymoPURE 96 Plasmid Miniprep Kit

Rapidly perform 96 Transfection-Grade Plasmid Minipreps Simultaneously

High-throughput purification of transfection-grade plasmid DNA from up to 5 ml of overnight E. coli culture using a vacuum manifold or centrifuge.

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Custom & OEM Solutions

Your Custom and OEM Solutions Partner

Zymo Research experts work closely with you to facilitate your custom manufacturing needs and bring your vision to life with ISO 9001 and ISO 13485 capabilities.

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