Comprehensive & User-Friendly Report
Let Us Do the Work.
Publication-Ready Data at Your Fingertips
All ZymoBIOMICS Services include comprehensive bioinformatics and statistical analyses for each microbiomics project. The report can be customized according to each unique project or application. Let Zymo Research do the bioinformatics so that you don’t have to!
Cited in Major Publications
Read peer-reviewed citations to discover how scientists are using these services.
Bullman et al. used the ZymoBIOMICS Targeted Sequencing Service to show that Fusobacterium and other pathogenic microbes are frequently found in both the primary and distant metastatic sites of the most aggressive and deadliest colon cancers. The authors demonstrated the potential for antibiotics to help fight fusobacterium-positive metastatic colon cancer in a mouse model containing patient derived xenografts.
Akyol et al. performed 16S and 18S analysis of anaerobic digestates using the ZymoBIOMICS Targeted Sequencing Service to assess microbial diversity in lignocellulose-rich digestates. The most abundant bacterial and fungal genera were consistent across digestate samples.
The authors investigated the role of the mucosal immune system, the commensal gut microbiota, and the intestinal epithelium in the loss of intestinal homeostasis that drives inflammatory bowel disease (IBD). The ZymoBIOMICS Targeted Sequencing Service was used to determine altered microbiome diversity in mice with different types of inflammation and to demonstrate that rapamycin, the drug used to inhibit mTOR signaling in mice in vivo, did not affect the commensal gut microbiota.
Improving the methane production and energy yield of biogas reactors by fungal bioaugmentation was investigated in this research. Results from testing with the ZymoBIOMICS Targeted Sequencing Service revealed that both fungal bioaugmentation and the different use of either whole crop or crop residues influenced the composition of the bacterial community in the reactors, with several taxa only identified in the bioaugmented samples, but that neither factor influence the methanogenic archaea composition, even though the methane yield in bioaugmented samples increased by 15-33%.
The authors investigated the microbial pools associated with landfill reactors that are impacted by nanomaterials. Using the ZymoBIOMICS Targeted Sequencing Service, they discovered that the bacterial communities were similar between control reactors and nanomaterial-containing reactors, but the archaea communities were highly different.
This study investigated how varying interchange ratios in wastewater treatment affects microbial community composition. Sample analysis via the ZymoBIOMICS Targeted Sequencing Service demonstrated that the relative abundance of the phyla Proteobacteria, Acidobacteria, and Bacteroidetes varied according to the interchange ratio and that the species of Thiothrix were highly abundance in all samples, revealing their potential importance to wastewater treatment processes.
This study is the first to investigate the bacterial community of the egg parasitoid Telenomus tridentatus. Using the ZymoBIOMICS Targeted Sequencing Service, Ramírez-Ahuja et al. showed the gut bacterial community of this parasitoid wasp is dominated by Proteobacteria and Actinobacteria and lay the groundwork for future studies regarding the role of bacterial communities in wasp species.
Any sample. Ultra-clean. Rigorous controls.
Human samples, water, soil, food testing , pathogen surveillance
Low Bioburden Reagents limit sample contamination.
Zymo's mock communities deemed "Regulatory-grade genomes" by FDA
Reliable and Unmatched Sample Processing
Zymo Research was the first company to develop microbiomics solutions, from collection to conclusion, based on new rigorous standards for microbiome measurements. Zymo Research is leading the initiative to improve reproducibility and accuracy in the field by developing the first commercially available microbiome standards. The FDA has accepted the ZymoBIOMICS Microbial Community standards as Regulatory-Grade Genomes in the Database for Reference Grade Microbial Sequences (FDA-ARGOS).The standards are utilized to develop and optimize every step of the microbiomics workflow, ensuring high-quality, unbiased results.
Unbiased Microbiome Profiling
Microbiome Standards Included in Every Project.
All Sources of Bias Taken Into Account
Preserve Microbiome Samples at Ambient Temperature with DNA/RNA Shield
Controlling PCR Chimera during 16S Library Preparation
Redefining targeted sequencing
Species-Level Resolution with 16S Sequencing.
Reshape the Coverage of 16S Primers
ZymoBIOMICS Shotgun Service
Take your samples further.
ZymoBIOMICS Shotgun Service
Shotgun metagenomic sequencing offers strain-level resolution, multiple-kingdom identification, and functional profiling.
In partnership with CosmosID, Zymo Research provides the most complete and sophisticated solution for shotgun metagenomics. The bioinformatics analysis for the ZymoBIOMICS Shotgun Service features:
- Identification with industry-leading sensitivity and precision
- Strain-level resolution of all microbial kingdoms (bacteria, archaea, viruses, protists, fungi)
World’s largest curated and customizable databases
- 150,000+ genomes and gene sequences
- 100s of millions of biomarkers
- Data structure follows the phylogenetic hierarchy of genomes, enabling accurate classification, even of unknown strains, based on this virtual tree of life
|Target Organisms||Sequencing Platform||Price Per Sample*|
|ZymoBIOMICS Targeted Sequencing Service: 16S(V1-V2, V3-V4, V4, or V6-V8)||Bacteria, Archaea||Illumina MiSeq||≤ $100|
|ZymoBIOMICS Targeted Sequencing Service: ITS||Fungi||Illumina MiSeq||≤ $100|
|ZymoBIOMICS Targeted Sequencing Service: 18S||Eukaryotes||Illumina MiSeq||≤ $100|
|ZymoBIOMICS Shotgun Metagenomic Service||Bacteria, Viruses, Fungi, Protists||Illumina HiSeq||≤ $300|