Quick COVID-19 Antibody Detection Kit
SARS-CoV-2 RBD-antigen is a highly specific target minimizing the risk of false positives caused by cross-reaction with other respiratory viruses.
2.5 hours from sample set up to results with equipment as little as an incubator and a plate reader.
Positive and Negative Controls are based on real human serum. Cut-off Control defines threshold between positive and negative samples.
An affordable solution for antibody detection.
The Quick COVID-19 Antibody Detection Kit features the receptor-binding domain (RBD) as target antigen. The RBD is a sub-domain of the SARS-CoV-2 Spike (S) protein. The initial contact between virus and human cells is established via the RBD, by that starting the cascade that allows SARS-CoV-2 to enter and infect the human host. Antibodies that specifically bind the RBD can cover this interaction site, thus preventing the virus from entering cells. Accordingly, the presence of RBD-specifc antibodies in a patient‘s plasma/serum correlates with their ability to neutralize the virus which in turn mediates immunity against SARS-CoV-2.
Additionally, the RBD-antigen captures antibodies specific for SARS-CoV-2 and is not prone to cross-reactivity with antibodies against other viruses (e.g. seasonal coronaviruses).
The Quick COVID-19 Antibody Detection Kit is designed for application in a standard molecular biology laboratory. You just need an incubator at 37° C and a 96-well plate reader to run the Quick COVID-19 Antibody Detection Kit in your lab.
The Quick COVID-19 Antibody Detection Kit contains three controls that simplify validation and evaluation of your test run. Positive and Negative Control both contain real human serum, and yield results typcially obtained for positive and negative patients, respectively. The Cut-off Control defines the threshold between positive and negative samples, and has been calibrated with over 200 patient samples during Quick COVID-19 Antibody Detection Kit development.
Premkumar et al (2020) Science Immunology 5(48), eabc8413; Robbiani et al (2020) Nature 584, 437-442; Manners et al (2020) Cureus 12(6), e8399